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White agaric supplement
White agaric supplement
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Agarikon 50% Polysaccharides
Immune system, fatigue and infections
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35.00 €(36.88 US$)
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Description
An immunity-boosting mushroom, referred to as the ‘elixir of long life’ in ancient Greece
  • High-quality extract of agarikon mushroom (also known as white agaric or larch polypore).
  • Supports the immune and respiratory systems.
  • Has antiviral and antibacterial properties.
  • Standardised to 50% polysaccharides for maximum efficacy.
  • The mycelium of agarikon is more digestible and bioavailable than other parts of the mushroom.
  • Used in popular apothecary for thousands of years.
  • Provides 1000 mg of agarikon mycelium extract per daily dose.
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Agarikon or white agaric on larch

Agarikon 50% Polysaccharides - Extract of white agaric - Reviews

Agarikon 50% Polysaccharides is a supplement containing larch polypore (agarikon or white agaric). Used for thousands of years, and in many parts of the world, this mushroom was described in the 1st century AD as the ‘elixir of long life‘ by the Greek physician Dioscorides for its positive effect on the immune defences and respiratory system.

As its name indicates, Agarikon 50% Polysaccharides is standardised to 50% polysaccharides in order to deliver maximum health benefits. It is listed under our Immunity category.

What is the agarikon mushroom (Laricifomes officinalis) or white agaric?

Agarikon, also known as larch polypore or white agaric (its scientific names are Laricifomes officinalis, Fomitopsis officinalis or Agaricum officinalis), is a mushroom from the Fomitopsidaceae family. It grows on decaying wood on larch trees and other conifers native to Europe, Morocco, Asia and North America.

Agarikon is shaped like a wide column or large hoof. It can weigh as much as 10kg and survive for up to 75 years. Soft and yellowy-white to start with, the mushroom then becomes hard and chalky before its flesh splits, and it takes on grey, brown or red hues.

Agarikon has been used for thousands of years to produce textiles, ritual masks, medicinal potions (1)... The Tlingit, Haida and other indigenous peoples of North America called it the ‘bread of ghosts’. They even believed that a certain Mushroom-Man – half-human, half-polypore – played a key role in the emergence of mankind. In Europe, larch polypore was traditionally used as a tonic to support the body’s natural defences, to treat lung disorders, and as a purgative and antiperspirant for soothing TB-related fevers (2-3), etc. In 19th century India, it was recommended for relieving spasmodic coughs (4).

What benefits are offered by Agarikon 50% Polysaccharides?

Agarikon is nutritionally very rich, and extremely good for the body. This agarikon extract thus contains:

  • coumarins, aromatic substances with antibacterial properties found in certain plants (5) ;
  • lanostane triterpenoids, phytochemicals that play an important part in many traditional herbalist remedies. They are notable for having trypanocidal effects (the ability to eliminate certain parasites) (6) ;
  • and most importantly, polysaccharides, complex carbohydrates that play a key role in forming organic structures and support tissues, particularly in plants. High in dietary fibre, they form gels and promote fluidification and lubrication. Some polysaccharides are able to interact with macrophages and to bind to viral proteins. In so doing, they form complexes which stop viruses entering cells and prevent infections (7). Several studies have shown agarikon to be an effective anti-viral against the smallpox, flu and hepatitis viruses (8). The cytotoxic properties of polysaccharides also help to prevent the proliferation of deviant cells (9-11) ;
  • agarikon extract also contains organic acids, anti-inflammatory phenolic compounds, etc. (12)

Why choose this particular agarikon (white agaric) supplement?

Agarikon 50% Polysaccharides is standardised to 50% polysaccharides allowing you to gain maximum benefit from the mushroom’s most powerful substances.

In addition, this supplement is made exclusively from extract of mycelium, the network of fungal filaments specific to mushrooms. This is the most digestible and absorbable part of larch polypore.

As you can see, agarikon is not just any mushroom: it is referred to in the Vienna Codex (dating from 542 AD), one of the oldest examples of Discorides’ medical manual, used for a long time in hospitals. Although mushrooms were often excluded from modern Western medicine, Laricifomes officinalis still appears in Feldman’s 'Formulaire pratique de pharmacologie' (1978). It is known as the ‘pharmacists’ agaric’ and remains part of the Croatian pharmacopeia as an antimicrobial (13-15), and is even being used in dermocosmetics for its anti-wrinkle benefits (16).

3 tips for boosting your immune system naturally

If you’re keen to boost your immunity naturally, adopt the following everyday measures:

  • relax and practise meditation. This stress-busting technique is known to reduce chronic inflammation, protect the intestinal barrier and boost immunity (17-18) And make sure you get enough sleep (19) ;
  • eat a varied, balanced diet, rich in micronutrients good for the immune system: vitamins C and D, zinc (20)... Conversely, avoid fast-release sugars (biscuits, pastries, sweets...) that feed bacteria and impair function of the parasympathetic system, which causes ear, nose and throat congestion, and encourages germs to multiply (21) ;
  • support your gut, as it also boosts your natural defences. Remember that 70% of the body’s immune cells are found in the gut microbiota. Focus on exercise, consuming ginger and other methods of improving digestive comfort and gut health (22-23).

Mushrooms, a future therapeutic solution

Mushrooms are a genuine natural treasure - nutritionally, gastronomically, ecologically, and medically. Yet this fantastic resource remains, for the most part, poorly understood and under-explored.

We do know that many of them promote good immunity, act against bacteria, viruses and tumours, have anti-inflammatory effects, help to regulate cholesterol levels, etc. Indeed, they are widely used to prevent and treat health problems in Asian countries.

Paul Stamets, a renowned American mycologist, is exploring the many roles mushrooms may play in the future, and especially the therapeutic properties of their mycelium. He’s responsible for a great many clinical studies on the subject. A strong advocate for biodiversity, Paul Stamets campaigns, in particular, for the preservation of ancient forests which he describes as a “veritable mushroom reservoir […] which could prevent pandemics – now and in the future”. He regularly promotes the preventive and therapeutic use of agarikon (24).

3 synergistic supplements to take with agarikon extract

Alongside your course of white agaric, consider taking shiitake (Lentinus edodes), another immunostimulant mushroom. But instead of taking a powder or ordinary shiitake extract, try AHCC®, an excellent polysaccharide made from the mushroom’s mycelium (25). Developed in Sapporo in Japan by the famous laboratory Amino Up Chemical Co., the shiitake supplement AHCC is standardised to 10% alpha-glucans and is easily absorbed by the body.

Another natural product, colostrum, or liquid gold, is the first form of mother’s milk that female mammals produce for their new-borns. Its nutritional virtues are exceptional: bovine colostrum is rich in fatty acids, vitamins, zinc (good for the immune system) and above all, IgG immunoglobulins (26). So to boost your immunity, combine your agarikon supplementation with colostrum capsules standardised to 30% IgG immunoglobulins.

Last but not least, if you want to look after your respiratory health, choose an extract of maritime pine bark and curcuminoids (27-28). You’ll find both in the tailor-made synergistic formulation Lung Detox, which is also rich in anti-inflammatory quercetin, sinus-protecting bromelain and antioxidant EGCg.

Composition
Daily dose: 2 tablets
Number of doses per pack: 30
Amount per dose
Extract of agarikon mycelium (Laricifomes officinalis) standardised to 50% polysaccharides 1000 mg
Other ingredients: acacia gum.
Directions for use

Adults. Take 2 tablets a day.

Each tablet contains 500 mg of extract of agarikon mycelium (Laricifomes officinalis) standardised to 50% polysaccharides.

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References
  1. Grienke U, Zöll M, Peintner U, Rollinger JM. European medicinal polypores--a modern view on traditional uses. J Ethnopharmacol. 2014 Jul 3;154(3):564-83. doi: 10.1016/j.jep.2014.04.030. Epub 2014 Apr 28. PMID: 24786572.
  2. Reddy DS, Kongot M, Kumar A. Coumarin hybrid derivatives as promising leads to treat tuberculosis: Recent developments and critical aspects of structural design to exhibit anti-tubercular activity. Tuberculosis (Edinb). 2021 Mar;127:102050. doi: 10.1016/j.tube.2020.102050. Epub 2021 Jan 6. PMID: 33540334.
  3. Rampin M. Champignons « médicinaux » : de l’usage traditionnel aux compléments alimentaires [Internet] [exercice]. [France]: Université Toulouse lll - Paul Sabater; 2017 [cité 9 janv 2019]. Disponible sur: htp://thesesante.ups-tlse.fr/1809/
  4. https://www.luminessens.org/post/2018/08/07/le-polypore-du-mélèze
  5. Girometta C. Antimicrobial properties of Fomitopsis officinalis in the light of its bioactive metabolites: a review. Mycology. 2018 Oct 25;10(1):32-39. doi: 10.1080/21501203.2018.1536680. PMID: 30834150; PMCID: PMC6394315.
  6. Girometta C. Antimicrobial properties of Fomitopsis officinalis in the light of its bioactive metabolites: a review. Mycology. 2018 Oct 25;10(1):32-39. doi: 10.1080/21501203.2018.1536680. PMID: 30834150; PMCID: PMC6394315.
  7. Shahzad F, Anderson D, Najafzadeh M. The Antiviral, Anti-Inflammatory Effects of Natural Medicinal Herbs and Mushrooms and SARS-CoV-2 Infection. Nutrients. 2020 Aug 25;12(9):2573. doi: 10.3390/nu12092573. PMID: 32854262; PMCID: PMC7551890.
  8. Vazirian M, Faridfar S, Eftekhari M. "Gharikon"/"Agharikon" a Valuable Medicinal Mushroom in Iranian Traditional Medicine. Iran J Med Sci. 2016 May;41(3 Suppl):S34. PMID: 27840500; PMCID: PMC5103541.
  9. Muszyńska B, Fijałkowska A, Sułkowska-Ziaja K, Włodarczyk A, Kaczmarczyk P, Nogaj E, Piętka J. Fomitopsis officinalis: a Species of Arboreal Mushroom with Promising Biological and Medicinal Properties. Chem Biodivers. 2020 Jun;17(6):e2000213. doi: 10.1002/cbdv.202000213. Epub 2020 May 28. PMID: 32271491.
  10. Durgo K, Koncar M, Komes D, Belscak-Cvitanovic A, Franekic J, Jakopovich I, Jakopovich N, Jakopovich B. Cytotoxicity of blended versus single medicinal mushroom extracts on human cancer cell lines: contribution of polyphenol and polysaccharide content. Int J Med Mushrooms. 2013;15(5):435-48. doi: 10.1615/intjmedmushr.v15.i5.20. PMID: 24266369.
  11. Jakopovic B, Oršolić N, Kraljević Pavelić S. Antitumor, Immunomodulatory and Antiangiogenic Efficacy of Medicinal Mushroom Extract Mixtures in Advanced Colorectal Cancer Animal Model. Molecules. 2020 Oct 28;25(21):5005. doi: 10.3390/molecules25215005. PMID: 33126765; PMCID: PMC7663060.
  12. Muszyńska B, Fijałkowska A, Sułkowska-Ziaja K, Włodarczyk A, Kaczmarczyk P, Nogaj E, Piętka J. Fomitopsis officinalis: a Species of Arboreal Mushroom with Promising Biological and Medicinal Properties. Chem Biodivers. 2020 Jun;17(6):e2000213. doi: 10.1002/cbdv.202000213. Epub 2020 May 28. PMID: 32271491.
  13. Guiot B. Les intérêts pharmacologiques du polypore « Laricifomes ofcinalis » [Internet]. [France]: Lille; 2016 [cité 18 janv 2019]. Disponible sur: htps://pepite-depot.univ-lille2.fr/nuxeo/site/esupversions/a20740d1-ba29-4801-8a22-fcb3456a6884
  14. Grienke U, Zöll M, Peintner U, Rollinger JM. European medicinal polypores - a modern view on traditonal uses. J Ethnopharmacol. 3 juill 2014;154(3):564-83.
  15. Jakopovich I. New dietary supplements from medicinal mushrooms: Dr Myko San--a registraton report. Int J Med Mushrooms. 2011;13(3):307-13.
  16. N. Santana M, M.C. Oliveira G, Hanai-Yoshida V, Oshima-Franco Y. Naturally Occurring Ingredients as Potential Antiaging Cosmetics. Vol. 30. 2011. 1531 p.
  17. Black DS, Slavich GM. Mindfulness meditation and the immune system: a systematic review of randomized controlled trials. Ann N Y Acad Sci. 2016 Jun;1373(1):13-24. doi: 10.1111/nyas.12998. Epub 2016 Jan 21. PMID: 26799456; PMCID: PMC4940234.
  18. Househam AM, Peterson CT, Mills PJ, Chopra D. The Effects of Stress and Meditation on the Immune System, Human Microbiota, and Epigenetics. Adv Mind Body Med. 2017 Fall;31(4):10-25. PMID: 29306937.
  19. Besedovsky L, Lange T, Born J. Sleep and immune function. Pflugers Arch. 2012 Jan;463(1):121-37. doi: 10.1007/s00424-011-1044-0. Epub 2011 Nov 10. PMID: 22071480; PMCID: PMC3256323.
  20. Gombart AF, Pierre A, Maggini S. A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients. 2020 Jan 16;12(1):236. doi: 10.3390/nu12010236. PMID: 31963293; PMCID: PMC7019735.
  21. Fajstova A, Galanova N, Coufal S, Malkova J, Kostovcik M, Cermakova M, Pelantova H, Kuzma M, Sediva B, Hudcovic T, Hrncir T, Tlaskalova-Hogenova H, Kverka M, Kostovcikova K. Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling. Cells. 2020 Dec 16;9(12):2701. doi: 10.3390/cells9122701. PMID: 33339337; PMCID: PMC7766268.
  22. Peters HP, De Vries WR, Vanberge-Henegouwen GP, Akkermans LM. Potential benefits and hazards of physical activity and exercise on the gastrointestinal tract. Gut. 2001 Mar;48(3):435-9. doi: 10.1136/gut.48.3.435. PMID: 11171839; PMCID: PMC1760153.
  23. Bode AM, Dong Z. The Amazing and Mighty Ginger. In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 7.Available from: https://www.ncbi.nlm.nih.gov/books/NBK92775/
  24. https://radiovictoria.ca/actualites/la-cle-pour-lutter-contre-les-futures-pandemies%E2%80%89-les-forets-anciennes-dit-le-gourou-des-champignons-paul-stamets/
  25. Shin MS, Park HJ, Maeda T, Nishioka H, Fujii H, Kang I. The Effects of AHCC®, a Standardized Extract of Cultured Lentinura edodes Mycelia, on Natural Killer and T Cells in Health and Disease: Reviews on Human and Animal Studies. J Immunol Res. 2019 Dec 20;2019:3758576. doi: 10.1155/2019/3758576. PMID: 31930148; PMCID: PMC6942843.
  26. Arslan A, Kaplan M, Duman H, Bayraktar A, Ertürk M, Henrick BM, Frese SA, Karav S. Bovine Colostrum and Its Potential for Human Health and Nutrition. Front Nutr. 2021 Jun 21;8:651721. doi: 10.3389/fnut.2021.651721. PMID: 34235166; PMCID: PMC8255475.
  27. Xia YF, Zhang JH, Xu ZF, Deng XM. Pycnogenol, a compound isolated from the bark of pinus maritime mill, attenuates ventilator-induced lung injury through inhibiting NF-κB-mediated inflammatory response. Int J Clin Exp Med. 2015 Feb 15;8(2):1824-33. PMID: 25932110; PMCID: PMC4402757.
  28. Lelli D, Sahebkar A, Johnston TP, Pedone C. Curcumin use in pulmonary diseases: State of the art and future perspectives. Pharmacol Res. 2017 Jan;115:133-148. doi: 10.1016/j.phrs.2016.11.017. Epub 2016 Nov 22. PMID: 27888157.

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