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Echinacea supplement for boosting the immune system
Echinacea supplement for boosting the immune system
0810Echinacea supplement for boosting the immune system
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Immunity Booster
Immunity
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Description
A formulation rich in organic echinacea, for boosting the immune and respiratory systems
  • Contains extract of echinacea, an organically-grown medicinal super-plant.
  • Echinacea purpurea is known to help boost the immune system and improve the health of the respiratory tract.
  • It has been used for centuries by Native Americans and European herbalists.
  • Also contains beta-(1,3/1,6)-glucans obtained from an extract of Saccharomyces cerevisiae known to help stimulate immunity.
  • Has a high content of vitamin C obtained from organic acerola cherry extract, which helps boost the immune defences.
  • Contains two active and complementary forms of zinc, which also play a role in optimal immune system function.
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Pink flowers of the immunostimulant plant echinacea

Immunity Booster, a multi-beneficial echinacea supplement

Immunity Booster is a dietary supplement of exceptional quality formulated to help boost the immune defences. It has been carefully developed over a long period by the SuperSmart team.

This brand new formulation combines an extract of organic echinacea (a medicinal plant known to both support the body’s natural defence system and help soothe sore throats), beta-glucans from Saccharomyces cerevisiae (polysaccharides recognised for improving immunity), vitamin C and zinc (both of which contribute to good immune system function) (1-4).

All these compounds have been selected to act synergistically and to provide you with the maximum benefit possible.

What exactly is in Immunity Booster?

The supplement thus contains 4 bioactive ingredients with particularly beneficial properties:

  1. extract of organically-grown echinacea (species Echinacea purpurea). Echinacea is a plant from the Asteraceae family, with fusiform roots and pink flowers. Native to the great plains of North America, this famous medicinal plant was used by Native Americans for treating colds, bronchitis, ‘flu and respiratory infections. It was subsequently introduced into Europe in 1895. The species Echinacea purpurea in particular, is highly valued by herbalists. It is today one of the most widely-used medicinal plants in Europe and North America. This purply-pink flowered echinacea is believed to support the body’s immune system function and to have a soothing effect on sore mouths and throats (5-6);
  2. beta-glucans from Saccharomyces cerevisiae (standardised to 70% beta-(1,3/1,6)-glucans). S accharomyces cerevisiae, or baker’s yeast, has been used for thousands of years, first by the Egyptians, Babylonians and Celts, to make bread, fermented drinks, kefir … This yeast is recognised for its high content of beta-glucans, immunostimulant polysaccharides which exist in the form of soluble dietary fibre(7);
  3. vitamin C from an extract of organic acerola. The acerola cherry is a tropical tree with glossy leaves and sour red fruit, also known as Barbados cherry or West Indian cherry. It is an important natural source of vitamin C. As we know, vitamin C is an essential nutrient with a particular ability to improve our immune defences (8);
  4. zinc. An essential trace element, zinc – like vitamin C – helps to boost the immune system. There are two complementary forms of this key nutrient in Immunity Booster. The first, an organic form called zinc gluconate, contains the zinc salt of gluconic acid, and is characterised by its long shelf life. The second, an inorganic compound called zinc sulfate, contains a zinc salt of sulfuric acid. It is generally used to help prevent zinc deficiency (which can adversely affect immunity, skin, hair ...) (9)

Benefits offered by Immunity Booster’s ingredients

The various benefits provided by the compounds in Immunity Booster are as follows:

  • a key plant in phytotherapy, the Echinacea purpurea species has a high content of alkylamides, phenolic compounds, complex polysaccharides, alkaloids ... This bio-rich plant has thus traditionally been used to help keep the body’s natural defences functioning properly. It is known to help boost both innate and adaptive immunity. Several studies have suggested it has anti-inflammatory, antimicrobial and antiviral effects. Echinacea seems to work by promotingmacrophage and NK cell activity. One double-blind clinical study of 473 subjects infected with ’flu found that an echinacea-based tea was as effective as some antivirals, and produced fewer side-effects. With regard to irritation of the respiratory tract, Echinacea purpurea may also help to soothe the mouth, throat and pharynx and make the throat and vocal cords feel more comfortable. It may also help to maintain a healthy lower urinary tract (10-13) ;
  • extract of Saccharomyces cerevisiae is standardised to 70% beta-(1,3/1,6)-glucans in order to provide a good intake of polysaccharides. These compounds are also known to stimulate the immune system. Beta-glucans appear to exert an immunomodulatory effect on several types of cell: cytotoxic T lymphocytes, B lymphocytes, neutrophils ... They may help to ensure a better macrophage response and to activate secretion of cytokines (interleukins IL-1, IL-6 and IL-8), as well as to prevent upper respiratory tract disorders and infections. In addition, they may also be beneficial against allergies and uncontrolled cell growth (14-22);
  • vitamin C from acerola supports healthy function of the immune and nervous systems and protection of cells against oxidative stress. This powerful antioxidant plays a role in supporting antiviral immune response and in increasing cytotoxic T lymphocyte numbers in the body. Vitamin C is also involved in normal energy metabolism, normal psychological function and normal formation of collagen, the latter being essential for healthy bones, cartilage, blood vessels, skin, gums and teeth (23-26);
  • lastly, zinc supports normal function of the immune system and vision, and helps maintain healthy skin, hair and nails. It is also involved in the normal metabolism of vitamin A, carbohydrates and fatty acids, normal synthesis of proteins, and the protection of cells against oxidative stress. This mineral also plays a part in the process of cell division and helps to combat several chronic diseases associated with ageing (27-29).

How should this supplement be taken?

Take 1 tablet of Immunity Booster a day with a glass of water.

Contraindications for taking Immunity Booster

Because of its high echinacea content, this complement should not be taken by those suffering from auto-immune or progressive diseases, or those on steroids or immune suppressants.

4 tips for boosting your immune system naturally

Are you keen to improve your immune defences? Here are 4 tips guaranteed to help:

  1. reduce your stress levels. Excessive secretion of cortisol, also known as the stress hormone, can damage immune system function. So make sure you take the pressure off from time to time and relax;
  2. take regular exercise. Frequent (though not excessive) physical activity is known to stimulate immunity. Try, for example, to jog for two and a half hours a week, spread over three sessions;
  3. get enough sleep. Some studies have shown that fatigue can reduce the quality of the immune response;
  4. consume fermented foods and drinks (yogurt, pickles, sourdough bread, miso, milk or fruit kefir…) as they are good for gut flora - an important component of immunity.

Some synergistic supplements

To maximise the immunostimulant effects of Immunity Booster’s ingredients, there are other high-quality supplements you might want to take as well.

Alongside Immunity Booster, you could start taking Green Propolis, an excellent green propolis supplement. This natural substance, produced by bees to protect their hives, contains more than 300 exceptional nutrients. It is highly effective at helping to improve your immune defences.

In addition, we’d draw your attention to the benefits of probiotics, particularly Bacillus subtilis. This active strain (I-2745) comes in the form of DR Caps™ in order to ensure that these ‘good bacteria’ arrive in the gut intact. The aim of this supplement is to help support your immune system and protect you from infection.

Composition
Daily dose: 1 tablet
Number of doses per pack: 60

Amount
per dose

2:1 extract of organically-grown Echinacea purpurea 100 mg
Beta-(1,3/1,6)-glucan (from 215 mg of Saccharomyces cerevisiae extract standardised to 70% beta-(1,3/1,6)-glucan) 150 mg
Vitamin C (from 470 mg of organically-grown acerola extract standardised to 17% vitamin C) 80 mg
Zinc (from 34.85 mg of zinc gluconate and 13.72 mg of zinc sulfate) 10 mg
Other ingredients: acacia gum.
Directions for use
Adults. Take 1 tablet a day.
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References
  1. Catanzaro M, Corsini E, Rosini M, Racchi M, Lanni C. Immunomodulators Inspired by Nature: A Review on Curcumin and Echinacea. Molecules (Basel, Switzerland). 2018;23(11):2778. doi: 10.3390/molecules23112778. PubMed PMID: 30373170.
  2. Cross GG, Jennings HJ, Whitfield DM, Penney CL, Zacharie B, Gagnon L. Immunostimulant oxidized beta-glucan conjugates. Int Immunopharmacol. 2001;1(3):539-50. Epub 2001/05/23. doi: 10.1016/s1567-5769(00)00021-7. PubMed PMID: 11367537.
  3. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) ; Scientific Opinion on the substantiation of health claims related to vitamin C and reduction of tiredness and fatigue (ID 139, 2622), contribution to normal psychological functions (ID 140), regeneration of the reduced form of vitamin E (ID 202), contribution to normal energy-yielding metabolism (ID 2334, 3196), maintenance of the normal function of the immune system (ID 4321) and protection of DNA, proteins and lipids from oxidative damage (ID 3331) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 ; EFSA Journal 2010;8(10):1815 ; DOI: 10.2903/j.efsa.2010.1815
  4. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) ; Scientific Opinion on the substantiation of health claims related to zinc and function of the immune system (ID 291, 1757), DNA synthesis and cell division (ID 292, 1759), protection of DNA, proteins and lipids from oxidative damage (ID 294, 1758), maintenance of bone (ID 295, 1756), cognitive function (ID 296), fertility and reproduction (ID 297, 300), reproductive development (ID 298), muscle function (ID 299), metabolism of fatty acids (ID 302), maintenance of joints (ID 305), function of the heart and blood vessels (ID 306), prostate function (ID 307), thyroid function (ID 308), acid-base metabolism (ID 360), vitamin A metabolism (ID 361) and maintenance of vision (ID 361) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 ; EFSA Journal 2009; 7(9):1229 ; DOI: 10.2903/j.efsa.2009.1229
  5. Catanzaro M, Corsini E, Rosini M, Racchi M, Lanni C. Immunomodulators Inspired by Nature: A Review on Curcumin and Echinacea. Molecules (Basel, Switzerland). 2018;23(11):2778. doi: 10.3390/molecules23112778. PubMed PMID: 30373170.
  6. He-ci Yu, Matti Kaarlas, « Popularity, Diversity and Quality of Echinacea », dans Sandra Carol Miller, He-ci Yu, Echinacea: The genus Echinacea, CRC Press, 2014
  7. Cross GG, Jennings HJ, Whitfield DM, Penney CL, Zacharie B, Gagnon L. Immunostimulant oxidized beta-glucan conjugates. Int Immunopharmacol. 2001;1(3):539-50. Epub 2001/05/23. doi: 10.1016/s1567-5769(00)00021-7. PubMed PMID: 11367537.
  8. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) ; Scientific Opinion on the substantiation of health claims related to vitamin C and reduction of tiredness and fatigue (ID 139, 2622), contribution to normal psychological functions (ID 140), regeneration of the reduced form of vitamin E (ID 202), contribution to normal energy-yielding metabolism (ID 2334, 3196), maintenance of the normal function of the immune system (ID 4321) and protection of DNA, proteins and lipids from oxidative damage (ID 3331) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 ; EFSA Journal 2010;8(10):1815 ; DOI: 10.2903/j.efsa.2010.1815
  9. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) ; Scientific Opinion on the substantiation of health claims related to zinc and function of the immune system (ID 291, 1757), DNA synthesis and cell division (ID 292, 1759), protection of DNA, proteins and lipids from oxidative damage (ID 294, 1758), maintenance of bone (ID 295, 1756), cognitive function (ID 296), fertility and reproduction (ID 297, 300), reproductive development (ID 298), muscle function (ID 299), metabolism of fatty acids (ID 302), maintenance of joints (ID 305), function of the heart and blood vessels (ID 306), prostate function (ID 307), thyroid function (ID 308), acid-base metabolism (ID 360), vitamin A metabolism (ID 361) and maintenance of vision (ID 361) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 ; EFSA Journal 2009; 7(9):1229 ; DOI: 10.2903/j.efsa.2009.1229
  10. Catanzaro M, Corsini E, Rosini M, Racchi M, Lanni C. Immunomodulators Inspired by Nature: A Review on Curcumin and Echinacea. Molecules (Basel, Switzerland). 2018;23(11):2778. doi: 10.3390/molecules23112778. PubMed PMID: 30373170.
  11. Rauš K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an Echinacea-Based Hot Drink Versus in Influenza Treatment: A Randomized, Double-Blind, Double-Dummy, Multicenter, Noninferiority Clinical Trial. Curr Ther Res Clin Exp. 2015;77:66-72. doi: 10.1016/j.curtheres.2015.04.001. PubMed PMID: 26265958.
  12. Fu A, Wang Y, Wu Y, Chen H, Zheng S, Li Y, Xu X, Li W. Echinacea purpurea Extract Polarizes M1 Macrophages in Murine Bone Marrow-Derived Macrophages Through the Activation of JNK. J Cell Biochem. 2017;118(9):2664-71. Epub 2017/01/10. doi: 10.1002/jcb.25875. PubMed PMID: 28067413.
  13. See DM, Broumand N, Sahl L, Tilles JG. In vitro effects of echinacea and ginseng on natural killer and antibody-dependent cell cytotoxicity in healthy subjects and chronic fatigue syndrome or acquired immunodeficiency syndrome patients. Immunopharmacology. 1997;35(3):229-35. Epub 1997/01/01. doi: 10.1016/s0162-3109(96)00125-7. PubMed PMID: 9043936.
  14. Cross GG, Jennings HJ, Whitfield DM, Penney CL, Zacharie B, Gagnon L. Immunostimulant oxidized beta-glucan conjugates. Int Immunopharmacol. 2001;1(3):539-50. Epub 2001/05/23. doi: 10.1016/s1567-5769(00)00021-7. PubMed PMID: 11367537.
  15. Konopski Z, Rasmussen LT, Seljelid R, Eskeland T. Phagocytosis of β-1,3-D-Glucan-Derivatized Microbeads by Mouse Peritoneal Macrophages Involves Three Different Receptors. Scandinavian Journal of Immunology. 1991;33(3):297-306. doi: 10.1111/j.1365-3083.1991.tb01775.x.
  16. Rahar S, Swami G, Nagpal N, Nagpal MA, Singh GS. Preparation, characterization, and biological properties of β-glucans. J Adv Pharm Technol Res. 2011;2(2):94-103. doi: 10.4103/2231-4040.82953. PubMed PMID: 22171300.
  17. Underhill DM. Macrophage recognition of zymosan particles. J Endotoxin Res. 2003;9(3):176-80. Epub 2003/07/02. doi: 10.1179/096805103125001586. PubMed PMID: 12831459.
  18. Rakowska R, Sadowska A, Dybkowska E, Świderski F. Spent yeast as natural source of functional food additives. Rocz Panstw Zakl Hig. 2017;68(2):115-21. Epub 2017/06/26. PubMed PMID: 28646828.
  19. Tsiapali E, Whaley S, Kalbfleisch J, Ensley HE, Browder IW, Williams DL. Glucans exhibit weak antioxidant activity, but stimulate macrophage free radical activity. Free Radic Biol Med. 2001;30(4):393-402. Epub 2001/02/22. doi: 10.1016/s0891-5849(00)00485-8. PubMed PMID: 11182295.
  20. Yun C-H, Estrada A, Van Kessel A, Park B-C, Laarveld B. β-Glucan, extracted from oat, enhances disease resistance against bacterial and parasitic infections. FEMS Immunology & Medical Microbiology. 2003;35(1):67-75. doi: 10.1016/S0928-8244(02)00460-1.
  21. Seljelid R, Rasmussen LT, Larm O, Hoffman J. The protective effect of beta 1-3D-glucan-derivatized plastic beads against Escherichia coli infection in mice. Scand J Immunol. 1987;25(1):55-60. Epub 1987/01/01. doi: 10.1111/j.1365-3083.1987.tb01046.x. PubMed PMID: 3544199.
  22. Samuelsen AB, Schrezenmeir J, Knutsen SH. Effects of orally administered yeast-derived beta-glucans: a review. Mol Nutr Food Res. 2014;58(1):183-93. Epub 2013/09/11. doi: 10.1002/mnfr.201300338. PubMed PMID: 24019098.
  23. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) ; Scientific Opinion on the substantiation of health claims related to vitamin C and reduction of tiredness and fatigue (ID 139, 2622), contribution to normal psychological functions (ID 140), regeneration of the reduced form of vitamin E (ID 202), contribution to normal energy-yielding metabolism (ID 2334, 3196), maintenance of the normal function of the immune system (ID 4321) and protection of DNA, proteins and lipids from oxidative damage (ID 3331) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 ; EFSA Journal 2010;8(10):1815 ; DOI: 10.2903/j.efsa.2010.1815
  24. Carr AC, Maggini S. Vitamin C and Immune Function. Nutrients. 2017;9(11):1211. doi: 10.3390/nu9111211. PubMed PMID: 29099763.
  25. Kim Y, Kim H, Bae S, Choi J, Lim SY, Lee N, Kong JM, Hwang Y-I, Kang JS, Lee WJ. Vitamin C Is an Essential Factor on the Anti-viral Immune Responses through the Production of -α/β at the Initial Stage of Influenza A Virus (H3N2) Infection. Immune Netw. 2013;13(2):70-4. Epub 2013/04/30. doi: 10.4110/in.2013.13.2.70. PubMed PMID: 23700397.
  26. Jariwalla RJ, Harakeh S. Antiviral and immunomodulatory activities of ascorbic acid. Subcell Biochem. 1996;25:213-31. Epub 1996/01/01. PubMed PMID: 8821976.
  27. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) ; Scientific Opinion on the substantiation of health claims related to zinc and function of the immune system (ID 291, 1757), DNA synthesis and cell division (ID 292, 1759), protection of DNA, proteins and lipids from oxidative damage (ID 294, 1758), maintenance of bone (ID 295, 1756), cognitive function (ID 296), fertility and reproduction (ID 297, 300), reproductive development (ID 298), muscle function (ID 299), metabolism of fatty acids (ID 302), maintenance of joints (ID 305), function of the heart and blood vessels (ID 306), prostate function (ID 307), thyroid function (ID 308), acid-base metabolism (ID 360), vitamin A metabolism (ID 361) and maintenance of vision (ID 361) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 ; EFSA Journal 2009; 7(9):1229 ; DOI: 10.2903/j.efsa.2009.1229
  28. Roohani N, Hurrell R, Kelishadi R, Schulin R. Zinc and its importance for human health: An integrative review. J Res Med Sci. 2013;18(2):144-57. Epub 2013/08/06. PubMed PMID: 23914218; PMCID: PMC3724376.
  29. Wessels I, Maywald M, Rink L. Zinc as a Gatekeeper of Immune Function. Nutrients. 2017;9(12):1286. doi: 10.3390/nu9121286. PubMed PMID: 29186856.

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